021-51111890
购物车（）
sales@molnova.cn
Epristeride
CAS No. 119169-78-7
Epristeride ( —— )
产品货号. M33351 CAS No. 119169-78-7
Epristeride (ONO-9302) 是人类固醇 5α-还原酶异构体 2 的选择性，特异性和非竞争性抑制剂，具有口服活性。Episteride 对 SR 同工酶 2 具有抑制作用，Ki 值为 0.7-2 nM。Episteride 可用于前列腺增生和痤疮的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1881 | 有现货 |
|
| 10MG | ￥3126 | 有现货 |
|
| 25MG | ￥4910 | 有现货 |
|
| 50MG | ￥6752 | 有现货 |
|
| 100MG | ￥8811 | 有现货 |
|
| 200MG | ￥11880 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥2166 | 有现货 |
|
生物学信息
-
产品名称Epristeride
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Epristeride (ONO-9302) 是人类固醇 5α-还原酶异构体 2 的选择性，特异性和非竞争性抑制剂，具有口服活性。Episteride 对 SR 同工酶 2 具有抑制作用，Ki 值为 0.7-2 nM。Episteride 可用于前列腺增生和痤疮的研究。
-
产品描述Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne.
-
体外实验Epristeride has inhibitory effects for SR isoenzymes types 2 (SR2) with Ki values of 0.7-2 nM.
-
体内实验——
-
同义词——
-
通路Apoptosis
-
靶点Apoptosis
-
受体Apoptosis | Reductase
-
研究领域——
-
适应症——
化学信息
-
CAS Number119169-78-7
-
分子量399.57
-
分子式C25H37NO3
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (250.27 mM; 超声助溶 )
-
SMILES[H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C=C(CC[C@]12C)C(O)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.M A Levy, et al. Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. J Steroid Biochem Mol Biol. 1994 Feb;48(2-3):197-206.?
产品手册
关联产品
-
CDK8-IN-13
CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces Apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity.
-
PRDX1-IN-1
PRDX1-IN-1 is a selective inhibtor of PRDX1 with an IC50 value of 0.164 μM. PRDX1-IN-1 can be used in researches related to cancer.PRDX1-IN-1 promots intracellular ROS accumulation, and inhibits the proliferation, invasion and migration of cancer cells besides inducing apoptosis. PRDX1-IN-1 could be used in cancer research.
-
3,4,5-Trihydroxycinn...
3,4,5-Trihydroxycinnamic acid decyl ester 是一种高效的脂质吸收和积累抑制剂，具有抗肥胖作用。3,4,5-Trihydroxycinnamic acid decyl ester 是一种胰腺脂肪酶 (pancreatic lipase) 抑制剂，其 EC50 大约为 0.9 μM。
