Cyclosporin D

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.

Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.(In Vitro):Cyclosporine D inhibits Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.(In Vivo):Cyclosporine D is a potent inhibitor in vivo of phorbol ester TPA-induced biological effects in mouse skin.

Cyclosporine D inhibits Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.

Cyclosporine D is a potent inhibitor in vivo of phorbol ester TPA-induced biological effects in mouse skin.

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Apoptosis

IL Receptor

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63775-96-2

1216.64

C63H113N11O12

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (20.55 mM)

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Sequence:cyclo ({Aaa}-Val-{Sar}-Leu-Val-Leu-Ala-Ala-Leu-Leu-{d-Val})

(-20℃)

With Ice Pack

≥ 2 years