• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

β-Amyloid 1-17

CAS No. 186319-72-2

β-Amyloid 1-17 ( —— )

产品货号. M30199 CAS No. 186319-72-2

This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    β-Amyloid 1-17
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
  • 产品描述
    This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
  • 体外实验
    β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Membrane Transporter/Ion Channel
  • 靶点
    Beta Amyloid
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    186319-72-2
  • 分子量
    2068.2
  • 分子式
    C90H130N28O29
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    Sequence:{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Shi JM, et al. Dissecting the behaviour of β-amyloid peptide variants during oligomerization and fibrillation. Pept Sci. 2017 Nov;23(11):810-817.
产品手册
关联产品
  • β-Amyloid 31-35

    β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity. This synthetic peptide consists of amino acids 31 to 35 of beta amyloid protein.

  • Aducanumab

    Aducanumab (BIIB037) 是一种选择性靶向聚集的 β 淀粉样蛋白 (Aβ) 的人单克隆抗体。Aducanumab 显示出脑渗透性,能够用于阿尔茨海默病 (AD) 研究。

  • β-Amyloid 18-28

    Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting the amnestic effect of the triad.