IGF-I 24-41
CAS No. 135861-49-3
IGF-I 24-41 ( Insulin-like Growth Factor I (24-41) )
产品货号. M29823 CAS No. 135861-49-3
IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称IGF-I 24-41
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
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产品描述IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
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体外实验——
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体内实验IGF-I (24-41) (ICV; 200 ng dose; 2 μL; postnatal days 2, 4, and 7) regulates somatic growth and behavioral development. Animal Model:Mice of an outbred Swiss-derived strain (CD-l) weighing 30-33g (virgin males) or 28-30g (nulliparous females)Dosage:200 ng dose; 2 μL Administration:ICV; postnatal days (PND) 2, 4, and 7 Result:Increased the rate of ultrasonic calls of the pups measured on PND8.
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同义词Insulin-like Growth Factor I (24-41)
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通路Angiogenesis
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靶点IGF-1R
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number135861-49-3
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分子量2017.16
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分子式C88H133N27O28
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 50 mg/mL (24.79 mM助)
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SMILES——
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化学全称Sequence:{Tyr}{Phe}{Asn}{Lys}{Pro}{Thr}{Gly}{Tyr}{Gly}{Ser}{Ser}{Ser}{Arg}{Arg}{Ala}{Pro}{Gln}{Thr}
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Cys-Gly
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KW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
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Protonstatin-1
Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
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