Eleutheroside B1 ( —— )

产品货号. M29245 CAS No. 16845-16-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Eleutheroside B1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

刺五加苷 B1 通过 POLR2A 和 N-糖基化介导其抗流感活性。 Eleutheroside B1 抑制多种趋化因子基因和流感核蛋白 (NP) 基因的 mRNA 表达，并表现出低细胞毒性。抗病毒和抗炎活性。
产品描述

Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.(In Vitro):eleutheroside B1 may affect N?glycan biosynthesis, the chemokine signaling pathway, cytokine?cytokine receptor interaction and, in particular, may target the POLR2A to inhibit the production of influenza virus genes.
体外实验

Eeutheroside B1 (100?μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells. RT-PCR Cell Line:Virus-infected A549 cells Concentration:100?μg/ml Incubation Time:24 hours Result:The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.
体内实验

——
同义词

——
通路

Microbiology/Virology
靶点

Influenza Virus
受体

Influenza Virus
研究领域

——
适应症

——

计算器

产品手册

关联产品

BMY-27709

BMY-27709 is an influenza virus growth inhibitor with an IC50 value of 3-8 μM against A/WSN/33 virus growth and demonstrates inhibitory activity against certain subtypes of influenza viruses. BMY-27709 acts early in H1 and H2 virus infections by inhibiting hemagglutinin proteins but has no effect on H3 subtype viruses and influenza B/Lee/40 viruses.
Peramivir

Peramivir (RWJ-270201、BCX-1812) 是一种流感神经氨酸酶抑制剂，可防止新病毒颗粒的释放；用于治疗和预防甲型流感和乙型流感的抗病毒剂。
CEF7, Influenza Viru...

HLA-B*08 restricted influenza virus nucleoprotein epitope.