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Triazavirin
CAS No. 928659-17-0
Triazavirin ( Riamilovir sodium dihydrate )
产品货号. M16651 CAS No. 928659-17-0
Triazavirin（利阿米洛韦钠二水合物）是一种广谱抗病毒化合物，针对流感病毒、拉沙病毒、TBEV 和埃博拉病毒。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥236 | 有现货 |
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| 10MG | ￥378 | 有现货 |
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| 25MG | ￥686 | 有现货 |
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| 50MG | ￥1200 | 有现货 |
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| 100MG | ￥1737 | 有现货 |
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| 200MG | ￥2538 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥226 | 有现货 |
|
生物学信息
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产品名称Triazavirin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Triazavirin（利阿米洛韦钠二水合物）是一种广谱抗病毒化合物，针对流感病毒、拉沙病毒、TBEV 和埃博拉病毒。
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产品描述Triazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus; suppresses the replication of influenza virus in cell culture and in chicken chorioallantoic membranes, and protects mice from death caused by type A and B influenza viruses.(In Vitro):The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.(In Vivo):The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
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体外实验The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.
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体内实验The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
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同义词Riamilovir sodium dihydrate
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通路Microbiology/Virology
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靶点Influenza Virus
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受体Influenza Virus
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研究领域——
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适应症——
化学信息
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CAS Number928659-17-0
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分子量228.189
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分子式C5H4N6O3S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (436.76 mM)
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SMILESCSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
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化学全称7-(Methylthio)-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4(6H)-one sodium sodium dihydrate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Karpenko I, et al. Antimicrob Agents Chemother. 2010 May;54(5):2017-22.
2. Loginova SIa, et al. Antibiot Khimioter. 2007;52(11-12):18-20.
3. Loginova SIa, et al. Antibiot Khimioter. 2014;59(1-2):3-5.
产品手册
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