Xanthopurpurin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

黄紫嘌呤具有抗病毒活性。 Xanthopurpurin 可通过促进病毒诱导的 MA-104 细胞凋亡来有效抑制轮状病毒的增殖。黄紫嘌呤主要表现出对胶原蛋白诱导的血小板聚集的强烈抑制作用。

Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation.(In Vitro):The cytotoxicity of RCAP toward MA-104 cells was evaluated using the WST-8 assay. Colloidal gold method and real time polymerase chain reaction (qPCR) assay were used to confirm the findings of the antiviral assay. Then, 4',6-diamidino-2-phenylindole (DAPI) staining method was subsequently used to investigate the mode of death among the cells. And the representative components of aqueous extract were isolated and identified. It was shown that both the viability of MA-104 cells and the viral load were reduced with increasing concentration of the extract. DAPI staining showed that virus-induced apoptosis was the cause of the low cell viability and viral load, an effect which was accelerated with incubation in the aqueous herbal extract. The major compounds postulated to exhibit this activity were isolated from the aqueous herbal extract and identified to be compounds Xanthopurpurin and Vanillic Acid.

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Purpuroxanthin

Others

Platelet aggregation

Platelet aggregation

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518-83-2

240.214

C14H8O4

>98% (HPLC)

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Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1

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(-20℃)

With Ice Pack

≥ 2 years