• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Arjunolic acid

CAS No. 465-00-9

Arjunolic acid ( —— )

产品货号. M29092 CAS No. 465-00-9

阿朱诺酸具有抗氧化、抗炎、镇痛和抗胆碱酯酶(AChE 和 BuChE)活性,可能作为开发治疗阿尔茨海默病的创新多功能药物的有前景的靶点。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥4019 有现货
10MG ¥5605 有现货
25MG ¥8528 有现货
50MG ¥11439 有现货
100MG ¥14940 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥4456 有现货

生物学信息

  • 产品名称
    Arjunolic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    阿朱诺酸具有抗氧化、抗炎、镇痛和抗胆碱酯酶(AChE 和 BuChE)活性,可能作为开发治疗阿尔茨海默病的创新多功能药物的有前景的靶点。
  • 产品描述
    Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment.(In Vitro):The multifunctional therapeutic application of Arjunolic acid has already been documented by its various biological functions including antioxidant, anti-fungal, anti-bacterial, anticholinesterase, antitumor, antiasthmatic, wound healing and insect growth inhibitor activities. The scientific basis behind its therapeutic application as a cardioprotective agent in traditional medicine is justified by its ability to prevent myocardial necrosis and apoptosis, platelet aggregation, coagulation and lowering of blood pressure, heart rate, as well as cholesterol levels. Its antioxidant property coupled with metal chelating property (by its two hydroxyl groups) protects different organs from metal and drug-induced organ pathophysiology. Arjunolic acid also plays a beneficial role in the pathogenesis of diabetes and its associated complications. The mechanism of cytoprotection of Arjunolic acid, at least in part, results from the detoxification of reactive oxygen species (ROS) produced in the respective pathophysiology. In addition to its other biological functions, it also possesses vibrant insecticidal properties and it has the potential to be used as a structural molecular framework for the design of molecular receptors in the general area of supramolecular chemistry and nanochemistry. Esters of Arjunolic acid function as organogelators which has wide application in designing thermochromic switches and sensor devices. Arjunolic acid derived crown ether is an attractive candidate for the design of molecular receptors, biomimetics and supramolecular systems capable of performing some biological functions.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Apoptosis
  • 靶点
    IL Receptor
  • 受体
    IL Receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    465-00-9
  • 分子量
    488.709
  • 分子式
    C30H48O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (204.62 mM)
  • SMILES
    CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@@]34C)C2C1)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
关联产品
  • IL-2-IN-1

    IL-2-IN-1 是一种有效的 IL-2 抑制剂,IC50 值为 1978 nM。IL-2-IN-1 显示出抗增殖活性。

  • CP 424174

    CP 424174 是一种 IL-1β 翻译后加工抑制剂,IC50 为 210 nM。抑制成熟 IL-1β 的形成。间接抑制 NLRP3。具有体内活性和口服生物利用度。

  • Canakinumab

    Canakinumab (ACZ885) 是一种重组的人抗 IL-1β 单克隆抗体。Canakinumab 显示出对人类和绒猴 IL-1β 的 IC50 值为分别为 43.6 和 40.8 pM。Canakinumab 的作用模式是基于对 IL-1β 信号的中和,从而抑制与自身免疫性疾病相关的炎症。