3-O-Methylquercetin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

3-O-Mmethylquercetin 是一种选择性、竞争性的 PDE3/PDE4 抑制剂，对 PDE3 的抑制作用比对 PDE4 的抑制作用低，且 Km 值较低。

3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low Km value. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.(In Vitro):Formulations composed of octyldodecanol, egg lecithin, water (NE) and cetyl trimethyl ammonium bromide (CNE) were obtained by spontaneous emulsification. This procedure yielded monodisperse nanoemulsions exhibiting a mean droplet size of approximately 200-300 nm. Nanoemulsions were further characterized in terms of zeta-potential, surface tension, and morphology by transmission electron microscopy. The amount of flavonoids incorporated into nanoemulsions reached nearly 100% (at 1 mg/mL). The permeation studies were carried out using ear pig skin mounted in Franz diffusion cells.

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Apoptosis

IL Receptor

IL Receptor

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1486-70-0

316.265

C16H12O7

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (158.10 mM)

COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)c(O)c1

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(-20℃)

With Ice Pack

≥ 2 years