3-O-Methylgallic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

3,4-二羟基-5-甲氧基苯甲酸比花青素更有效地减少 Caco-2 细胞的细胞增殖 (IC50 = 24.1 μM)，并且可以在结肠癌在肠道中形成后提供针对结肠癌的保护。 3,4-二羟基-5-甲氧基苯甲酸抑制已知在结直肠癌中被激活的转录因子 NF-κB、AP-1、STAT-1 和 OCT-1。

3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.(In Vitro):3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability.

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3,4-Dihydroxy-5-methoxybenzoic acid | 3,4-Dihydroxy-5-methoxybenzoic acid

Apoptosis

Apoptosis

Apoptosis

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3934-84-7

184.147

C8H8O5

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (271.52 mM)

COc1cc(cc(O)c1O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years