Beta-mangostin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Beta-Mangostin (β-Mangostin) 是一种氧杂蒽酮化合物，具有抗菌和抗疟活性。

Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).(In Vitro):Beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest.

beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest.

——

β-Mangostin

Apoptosis

Apoptosis

Apoptosis

——

——

20931-37-7

424.493

C25H28O6

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (58.89 mM)

COc1cc2oc3cc(O)c(OC)c(CC=C(C)C)c3c(=O)c2c(O)c1CC=C(C)C

——

(-20℃)

With Ice Pack

≥ 2 years