021-51111890
购物车（）
sales@molnova.cn
Diloxanide
CAS No. 579-38-4
Diloxanide ( RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida )
产品货号. M27976 CAS No. 579-38-4
Diloxanide 是一种内阿米巴杀虫剂。它被认为是轻度肠阿米巴病或无症状囊肿患者的首选管腔化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥167 | 有现货 |
|
| 10MG | ￥236 | 有现货 |
|
| 25MG | ￥333 | 有现货 |
|
| 50MG | ￥462 | 有现货 |
|
| 100MG | ￥745 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥183 | 有现货 |
|
生物学信息
-
产品名称Diloxanide
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Diloxanide 是一种内阿米巴杀虫剂。它被认为是轻度肠阿米巴病或无症状囊肿患者的首选管腔化合物。
-
产品描述Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
-
体外实验——
-
体内实验Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
-
同义词RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida
-
通路Microbiology/Virology
-
靶点Parasite
-
受体TNNI3 Interacting Kinase (TNNI3K)
-
研究领域——
-
适应症——
化学信息
-
CAS Number579-38-4
-
分子量234.08
-
分子式C9H9Cl2NO2
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 33.33 mg/mL (142.39 mM)
-
SMILESCN(C(=O)C(Cl)Cl)c1ccc(O)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.
