Amperozide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Amperozide 是一种 5-HT2 拮抗剂。

Amperozide, a 5-HT2 antagonist, attenuates craving for cocaine by rats and reduces agonistic behaviors such as slashing and biting in pigs.(In Vitro):Amperozide inhibited the amphetamine-stimulated release of dopamine from perfused rat striatal tissue in a dose-dependent manner. With 1 and 10 microM amperozide there was significant inhibition of the amphetamine-stimulated release of dopamine, to 44 and 36% of control. In contrast, 10 microM amperozide significantly strengthened the electrically stimulated release of dopamine from perfused striatal slices. Amperozide 1-10 microM had no significant effect on the potassium-stimulated release of dopamine. 10 microM amperozide also slightly increased the basal release of 3H-dopamine from perfused striatal tissue.

——

——

FG 5606 | Amperozida | Amperozidum

Endocrinology/Hormones

5-HT Receptor

——

——

——

75558-90-6

401.5

C23H29F2N3O

>98% (HPLC)

——

O=C(N1CCN(CCCC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)CC1)NCC

——

(-20℃)

With Ice Pack

≥ 2 years