Navuridine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Navuridine 是一种口服活性 HIV 逆转录酶抑制剂，半衰期相对较短。

Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.

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Pharmacokinetic Parameters of 3′-Azido-2′,3′-dideoxyuridine in male Sprague-Dawley rats. Animal Model:Adult male Sprague-Dawley rats (300-400 g)Dosage:25, 100 mg/kg Administration:Intravenous bolus injection or oral gavage (Pharmacokinetic Analysis)Result:The oral bioavailability estimates of 3′-Azido-2′,3′-dideoxyuridine at doses of 25 and 100 mg/kg averaged 53%.

AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU

Microbiology/Virology

HIV

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84472-85-5

253.218

C9H11N5O4

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (987.32 mM)

OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O

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(-20℃)

With Ice Pack

≥ 2 years