2-Fluoroadenine
CAS No. 700-49-2
2-Fluoroadenine ( NSC 27364 | 2- Fluoro-6-Aminopurine )
产品货号. M27216 CAS No. 700-49-2
2-氟腺嘌呤对非增殖和增殖肿瘤细胞具有毒性。 2-氟腺嘌呤可用于抗癌研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 200MG | ¥122 | 有现货 |
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| 500MG | ¥176 | 有现货 |
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| 1G | ¥241 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥185 | 有现货 |
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生物学信息
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产品名称2-Fluoroadenine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述2-氟腺嘌呤对非增殖和增殖肿瘤细胞具有毒性。 2-氟腺嘌呤可用于抗癌研究。
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产品描述2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.(In Vitro):In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity.
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体外实验2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis.2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity in nonproliferating MRC-5 cells.2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses in Balb-3T3 cells incubated in serum-free medium. Cell Proliferation Assay Cell Line:CEM cells Concentration:2 μM Incubation Time:4 hours Result:Inhibited CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis.Cell Cytotoxicity Assay Cell Line:MRC-5 cells Concentration:0-1000 μM Incubation Time:4 hours Result:Exhibited cytotoxicity in nonproliferating MRC-5 cells.
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体内实验——
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同义词NSC 27364 | 2- Fluoro-6-Aminopurine
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通路Cell Cycle/DNA Damage
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靶点DNA/RNA Synthesis
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受体SARS-CoV
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研究领域——
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适应症——
化学信息
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CAS Number700-49-2
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分子量153.12
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分子式C5H4FN5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 20.83 mg/mL (136.04 mM)
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SMILESNc1[nH]c(F)nc2ncnc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Compound for treating diseases caused by coronavirus infection. Patent WO2018174442A1.
产品手册
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