N-Nitrosodiethylamine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

N-亚硝基二乙胺是一种强效的肝癌二烷基亚硝胺。 N-亚硝基二乙胺主要存在于水、烟草烟雾、切达干酪、腌制、油炸食品和许多酒精饮料中。 N-亚硝基二乙胺负责与 DNA 修复/复制相关的核酶的变化。

N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus.(In Vivo):Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease.

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Cell Cycle/DNA Damage

DNA/RNA Synthesis

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55-18-5

102.137

C4H10N2O

>98% (HPLC)

In Vitro:?H2O : 100 mg/mL (979.05 mM)

CCN(CC)N=O

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(-20℃)

With Ice Pack

≥ 2 years