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Xyloidone

CAS No. 15297-92-4

Xyloidone ( Dehydro-α-lapachone | NSC-106453 | NSC106453 | NSC 629748 | Dehydrolapachone | Dehydrolapachone | )

产品货号. M27202 CAS No. 15297-92-4

Xyloidone 具有抗真菌活性,在 0.4-33.3 mg/L 范围内可完全抑制 B. cinerea、Colletotrichum acutatum Simmonds、Colletotrichum gloeosporioides Simmonds、M. grisea 和 Pythium ultimum Trow 的菌丝生长。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1064 有现货
10MG ¥1568 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Xyloidone
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Xyloidone 具有抗真菌活性,在 0.4-33.3 mg/L 范围内可完全抑制 B. cinerea、Colletotrichum acutatum Simmonds、Colletotrichum gloeosporioides Simmonds、M. grisea 和 Pythium ultimum Trow 的菌丝生长。
  • 产品描述
    Xyloidone exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Trow over a range of 0.4-33.3 mg/L.(In Vitro):Xyloidone controlls the development of rice blast, tomato late blight, wheat leaf rust, barley powdery mildew and red pepper anthracnose (Colletotrichum coccodes (Wallr) S Hughes). Xyloidone is particularly effective in suppressing red pepper anthracnose by 95% at a concentration of 125 mg/L.(In Vivo):Xyloidone inhibits vessel regeneration, interferes with vessel anastomosis, and limits plexus formation in zebrafish. Xyloidone induces vascular pruning and growth delay in orthotopic mammary tumors in mice. Xyloidone targets cell adhesion by promoting ubiquitination of the Rho-GTPase Rac1, which is frequently up-regulated in many different cancers.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Dehydro-α-lapachone | NSC-106453 | NSC106453 | NSC 629748 | Dehydrolapachone | Dehydrolapachone |
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    NK1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    15297-92-4
  • 分子量
    240.258
  • 分子式
    C15H12O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC1(C)OC2=C(C=C1)C(=O)c1ccccc1C2=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Gackenheimer SL, et al. In vitro and ex vivo autoradiography of the NK-1 antagonist [3H]-LY686017 in Guinea pig brain. Neuropeptides. 2011 Apr;45(2):157-64.
产品手册
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