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Cefcapene Pivoxil Hydrochloride
CAS No. 147816-24-8
Cefcapene Pivoxil Hydrochloride ( —— )
产品货号. M19785 CAS No. 147816-24-8
Cefcapene Pivoxil 是头孢卡平的新戊酸酯前药形式，是一种具有抗菌活性的半合成第三代头孢菌素。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥113 | 有现货 |
|
| 10MG | ￥158 | 有现货 |
|
| 25MG | ￥275 | 有现货 |
|
| 50MG | ￥458 | 有现货 |
|
| 100MG | ￥659 | 有现货 |
|
| 200MG | ￥972 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Cefcapene Pivoxil Hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Cefcapene Pivoxil 是头孢卡平的新戊酸酯前药形式，是一种具有抗菌活性的半合成第三代头孢菌素。
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产品描述Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil the ester bond is cleaved releasing active cefcapene.(In Vivo):Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration.
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体外实验——
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体内实验Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration. Animal Model:Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×109 CFU)Dosage:100 mg/kg Administration:Oral administration; 100mg/kg; 4 days Result:Was against H. influenzae colonization in mouse lung.
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同义词——
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Inflammation/Immunology
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适应症Bacterial infections; Ophthalmic infections; Otorhinolaryngological infections; Respiratory tract infections; Skin and soft tissue infections
化学信息
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CAS Number147816-24-8
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分子量622.12
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分子式C23H29N5O8S2
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纯度>98% (HPLC)
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溶解度DMSO: 90 mg/mL
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SMILESO.Cl.CC\C=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)c1csc(N)n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Murakami M. Masuda K. Utsunomiya R. Oda F. Namba C. & Sayama K. (2015). Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.?Dermatology?231(4) 304-311. doi: 10.1159/000439401
产品手册
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