021-51111890
购物车（）
sales@molnova.cn
2-(Methylamino)-1H-purin-6(7H)-one
CAS No. 10030-78-1
2-(Methylamino)-1H-purin-6(7H)-one ( N2-methylguanine )
产品货号. M26576 CAS No. 10030-78-1
2-(Mmethylamino)-1H-purin-6(7H)-one 是人体体液中发现的一种内源性甲基化核苷，也是一种修饰核苷。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥847 | 有现货 |
|
| 10MG | ￥1378 | 有现货 |
|
| 25MG | ￥2306 | 有现货 |
|
| 50MG | ￥3329 | 有现货 |
|
| 100MG | ￥4617 | 有现货 |
|
| 200MG | ￥6237 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称2-(Methylamino)-1H-purin-6(7H)-one
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述2-(Mmethylamino)-1H-purin-6(7H)-one 是人体体液中发现的一种内源性甲基化核苷，也是一种修饰核苷。
-
产品描述2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.(In Vitro):2-(Methylamino)-1H-purin-6(7H)-one is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min. 2-(Methylamino)-1H-purin-6(7H)-one is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding.
-
体外实验2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding. 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min.
-
体内实验——
-
同义词N2-methylguanine
-
通路Cell Cycle/DNA Damage
-
靶点DNA/RNA Synthesis
-
受体CYP3A
-
研究领域——
-
适应症——
化学信息
-
CAS Number10030-78-1
-
分子量165.156
-
分子式C6H7N5O
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 1 mg/mL (6.06 mM)
-
SMILESCNc1nc(=O)c2[nH]cnc2[nH]1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Method for increasing HDL cholesterol levels?using?heteroaromatic phenylmethanes. United States Patent 6103733
