4-Vinylphenol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

4-乙烯基苯酚是白花蛇舌草中发现的葡萄酒中乳酸菌对香豆酸和阿魏酸的代谢产物。 4-乙烯基苯酚在体内诱导细胞凋亡。

4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.(In Vitro):4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis. 4-Vinylphenol (50, 100 μg/mL) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL. 4-Vinylphenol (0.15, 0.3 μg/mL) reduces sphere?formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells.

4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL. 4-Vinylphenol (0.15 or 0.3 μg/mL; 3 days) reduces sphere?formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol (50, 100 μg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis.

——

——

Apoptosis

Apoptosis

HCV NS5A

——

——

2628-17-3

120.151

C8H8O

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (832.29 mM)

Oc1ccc(C=C)cc1

——

(-20℃)

With Ice Pack

≥ 2 years