NH2-C2-NH-Boc

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

NH2-C2-NH-Boc (PROTAC Linker 22) 是一种基于烷基链的 PROTAC 连接体，可用于 PROTAC 的合成。 PROTAC 包含两个通过连接子连接的不同配体；一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。 PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白。

NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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PROTAC Linker 22

PROTACs

PROTAC

Alkyl-Chain

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57260-73-8

160.21

C7H16N2O2

>98% (HPLC)

In Vitro:?DMSO : ≥ 100 mg/mL (624.18 mM)

CC(C)(C)OC(=O)NCCN

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(-20℃)

With Ice Pack

≥ 2 years