Biotin-PEG3-acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Biotin-PEG3-acid 是一种生物素标记的、基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。Biotin-PEG3-acid 是一种含有羧酸基团的异生物功能生物素 PEG 衍生物。亲水性 PEG 间隔臂赋予水溶性，并转移至生物素化分子。

Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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PROTACs

PROTAC

PEGs

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252881-76-8

447.55

C19H33N3O7S

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (223.44 mM)

O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NCCOCCOCCOCCC(O)=O)=O)[H]

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(-20℃)

With Ice Pack

≥ 2 years