Velneperit ( S2367 )

产品货号. M22270 CAS No. 342577-38-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Velneperit
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Velneperit 是一种有效的选择性神经肽 Y (NPY) Y5 受体，正在评估其治疗肥胖的效果。
产品描述

Velneperit is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
体外实验

——
体内实验

——
同义词

S2367
通路

GPCR/G Protein
靶点

Neuropeptide Y Receptor
受体

neuropeptide Y (NPY) Y5 receptor
研究领域

Others
适应症

Obesity

1. George M , Rajaram M , Shanmugam E . New and emerging drug molecules against obesity.[J]. J Cardiovasc Pharmacol Ther, 2014, 19(1):65-76.

计算器

产品手册

关联产品

[cPP1-7,NPY19-23,Ala...

Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
CYM2503

CYM2503 是 GAL2 受体的正变构调节剂 (PAM)，可在体外增强甘丙肽诱导的 IP1 产生。
GR 231118

Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively). Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively). Suppresses food intake in rats in vivo. Also has affinity for neuropeptide FF (NPFF) receptors in vitro (Ki = 43-73 nM).