Ustekinumab
CAS No. 815610-63-0
Ustekinumab ( —— )
产品货号. M22144 CAS No. 815610-63-0
Ustekinumab 是一种抗 IL-12/IL-23 IgG1κ 人单克隆抗体。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥7999 | 有现货 |
|
| 10MG | ¥10735 | 有现货 |
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| 25MG | ¥14694 | 有现货 |
|
| 50MG | ¥20088 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ustekinumab
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ustekinumab 是一种抗 IL-12/IL-23 IgG1κ 人单克隆抗体。
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产品描述Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
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体外实验Ustekinumab is a human monoclonal antibody that prevents human IL-12 and IL-23 from binding to the IL-12Rβ1 receptor chain of IL-12 (IL-12Rβ1/β2) and IL-23 (IL-12Rβ1/23R) receptor complexes on the surface of natural killer cells and T-cells. Ustekinumab is a human IgG1 kappa (κ) monoclonal antibody against the IL-12/IL-23 p40 subunit that prevents its interaction with IL-12Rβ1, thereby blocking subsequent signaling. The FcRn affinities at pH 6.0 fell in a narrow range for all 11 antibodies. The equilibrium dissociation constant (KD) is calculated relative to Ustekinumab (Ustekinumab=1.0).
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体内实验——
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同义词——
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通路Apoptosis
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靶点IL Receptor
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受体IL Receptor
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研究领域——
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适应症——
化学信息
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CAS Number815610-63-0
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分子量148 kDa
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Montepaone M, et al. Profile of ustekinumab and its potential in the treatment of active psoriatic arthritis. Open Access Rheumatol. 2014 Feb 20;6:7-13.
产品手册
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