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OGG1-IN-O8
CAS No. 350997-39-6
OGG1-IN-O8 ( —— )
产品货号. M21645 CAS No. 350997-39-6
OGG1-IN-O8 是 8-氧代鸟嘌呤 DNA 糖基化酶 1 的抑制剂 (OGG1;IC50 : 0.35 μM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥469 | 有现货 |
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| 10MG | ￥798 | 有现货 |
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| 25MG | ￥1567 | 有现货 |
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| 50MG | ￥2353 | 有现货 |
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| 100MG | ￥3418 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥525 | 有现货 |
|
生物学信息
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产品名称OGG1-IN-O8
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述OGG1-IN-O8 是 8-氧代鸟嘌呤 DNA 糖基化酶 1 的抑制剂 (OGG1;IC50 : 0.35 μM)。
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产品描述OGG1-IN-O8 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1;IC50 : 0.35 μM).
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体外实验OGG1-IN-08 (50 μM) inhibits different DNA glycosylases activities, it inhibits?nei endonuclease VIII-like 1 DNA glycosylase (NEIL1)(84.56%), endonuclease III-like (NTH1)(63.09%), andFpg (91.74%), respectively.OGG1-IN-08 (10 μM) has a inhibitory OGG1 lyase activity on a substrate containing an AP site compared with the no inhibitor control.OGG1-IN-08 (10 μM) decreases the number of bases released into solution by OGG1 for both the 8-oxo-Gua and FapyGua compared with the no inhibitor.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体8-oxoguanine DNA glycosylase 1 (OGG1)
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研究领域——
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适应症——
化学信息
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CAS Number350997-39-6
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分子量261.12
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分子式C9H6Cl2N2OS
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (95.74 mM)
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SMILESNNC(=O)c1sc2cccc(Cl)c2c1Cl
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化学全称34-Dichloro-benzo[b]thiophene-2-carboxylic acid hydrazide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lloyd R.S. Mccullough A.K. and Donley N.?Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1).?(2016).
产品手册
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