Deruxtecan

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Deruxtecan 是一种 ADC 药物连接物缀合物，由 DX-8951 (DXd) 衍生物和马来酰亚胺-GGFG 肽连接物组成，用于合成 DS-8201 和 U3-1402。

Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.(In Vitro):Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window.

Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window.

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Others

Other Targets

E3 Ligase

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1599440-13-7

1034.068

C52H56FN9O13

>98% (HPLC)

In Vitro:?DMSO : 35 mg/mL (33.85 mM)

CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)COCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)c(c3Cn1c2=O)c45

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(-20℃)

With Ice Pack

≥ 2 years