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Enzalutamide carboxylic acid
CAS No. 1242137-15-0
Enzalutamide carboxylic acid ( —— )
产品货号. M21564 CAS No. 1242137-15-0
Enzalutamide fascia 是雄激素受体 (AR) 的拮抗剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥714 | 有现货 |
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| 5MG | ￥1264 | 有现货 |
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| 10MG | ￥1881 | 有现货 |
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| 25MG | ￥3050 | 有现货 |
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| 50MG | ￥4334 | 有现货 |
|
| 100MG | ￥6012 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1264 | 有现货 |
|
生物学信息
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产品名称Enzalutamide carboxylic acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Enzalutamide fascia 是雄激素受体 (AR) 的拮抗剂。
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产品描述Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
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体外实验Enzalutamide is converted into its major metabolites, N-desmethyl enzalutamide and carboxylic acid enzalutamide, by cytochrome P450 (CYP) 3A4/5 and CYP2C8, respectively. N-desmethyl enzalutamide has clinically relevant anti-androgen capacities similar to enzalutamide, whereas carboxylic acid enzalutamide is inactive.
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Androgen Receptor (AR)
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受体Androgen Receptor
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研究领域cancer
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适应症castration-resistant prostate cancer
化学信息
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CAS Number1242137-15-0
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分子量451.4
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分子式C20H13F4N3O3S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (276.92 mM)
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SMILESCC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(C(O)=O)c(F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.van Nuland M et al. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy. 2019 Dec;39(12):1137-1145.
