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JNJ 303
CAS No. 878489-28-2
JNJ 303 ( —— )
产品货号. M20998 CAS No. 878489-28-2
JNJ 303 是一种有效的 IK 阻断剂 (IC50 : 64 nM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥847 | 有现货 |
|
| 10MG | ￥1416 | 有现货 |
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| 25MG | ￥2911 | 有现货 |
|
| 50MG | ￥4166 | 有现货 |
|
| 100MG | ￥5688 | 有现货 |
|
| 200MG | ￥7668 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥844 | 有现货 |
|
生物学信息
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产品名称JNJ 303
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述JNJ 303 是一种有效的 IK 阻断剂 (IC50 : 64 nM)。
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产品描述JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
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体外实验JNJ 303 can block IKs with an IC50 value of 64 nM. JNJ 303 (3.3 μM) does not have any effects on other cardiac channels.JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).
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体内实验JNJ 303 recapitulates the Exn4-induced decrease in fasting blood glucose level in mice.
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同义词——
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体IKs
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研究领域——
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适应症——
化学信息
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CAS Number878489-28-2
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分子量440.98
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分子式C21H29ClN2O4S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 62.5 mg/mL (141.73 mM)
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SMILESCC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(NS(C)(=O)=O)(C3)C2
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化学全称2-(4-Chloro-phenoxy)-N-(5-methanesulfonylamino-adamantan-2-yl)-2-methyl-propionamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kang C Badiceanu A Brennan J A et al. β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle[J]. Scientific Reports 2017 7(1):15922.
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