Trimethobenzamide hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Trimethobenzamide Hydrochronic 是 D2 受体阻滞剂。三甲苯甲酰胺是一种止吐药，用于预防恶心和呕吐。

Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.(In Vitro):Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center.(In Vivo):The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration.

Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center.

The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration.

Ro 2-9578 | Tribenzagan Hydrochloride

GPCR/G Protein

Dopamine Receptor

D2

Others

Nausea and vomiting

554-92-7

424.92

C21H29ClN2O5

>98% (HPLC)

DMSO:≥100 mg/mL (235.34 mM)

Cl.COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1

——

(-20℃)

With Ice Pack

≥ 2 years