3-Ureidopropionic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

脲基丙酸是尿嘧啶代谢的中间体。更具体地说，它是二氢尿嘧啶的分解产物，由二氢嘧啶酶产生。

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.

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Ureidopropionic acid | Carbamoyl-b-alanine

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

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462-88-4

132.12

C4H8N2O3

>98% (HPLC)

DMSO:10 mM

NC(=O)NCCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years