L-Methionine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

L-蛋氨酸是蛋氨酸的L-异构体，蛋氨酸是人类发育必需的氨基酸。蛋氨酸起到肝脏保护剂的作用。

L-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.

Cell Proliferation Assay Cell Line:BXPC-3, HPAC Concentration:5 mg/mL Incubation Time:7 or 3 days Result:Reduced growth of BXPC-3 cells by 31 and 32%, respectively. Reduced growth of HPAC cells by 35% and 18%, respectively. Reduced S to G2 transition in BXPC-3 cells and intervened in both G1–S and S–G2 transitions in HPAC cells. Increased late cell apoptosis at a percentage of 76% in BXPC-3 cells.Western Blot Analysis Cell Line:ECV304 Concentration:0.3, 1, 3, 5, 10 mM Incubation Time:24 h Result:Increased the level of HO-1 protein up to 9.5-fold and the HO-1 activity.

Animal Model:Male Wistar rats (body weight 70-80 g) Dosage:215,268.8, 322.5, 430 mg/kg Administration:p.o.Result:Reduced the hepatic ROS levels and the hepatic MDA contents. Increased the hepatic T-AOC, CAT and T-SOD. Increased the hepatic activity of GCL, GR, GST and GPx.

L-Methionin | L(-)-Methionin

Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

Metabolic Disease

Nutritional fortifier acute hepatitis cirrhosis

63-68-3

149.21

C5H11NO2S

>98% (HPLC)

DMSO:10uM;Water:Soluble

CSCC[C@H](N)C(O)=O

L-methionine

(-20℃)

With Ice Pack

≥ 2 years