6-Thio-dG ( 6-thio-dG | 6thiodG | 6 thio dG | 6-Thio-2'-deoxyguanosine )

产品货号. M19108 CAS No. 789-61-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

6-Thio-dG
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

6-thio-dG 是一种核苷类似物和端粒酶底物。
产品描述

6-thio-dG is a telomerase substrate precursor with anticancer activities. In A549 lung cancer cell-based mouse xenograft studies, 6-thio-dG caused a decrease in the tumor growth rate superior to that observed with 6-thioguanine treatment. In addition, 6-thio-dG increased telomere dysfunction in tumor cells in vivo.
体外实验

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体内实验

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同义词

6-thio-dG | 6thiodG | 6 thio dG | 6-Thio-2'-deoxyguanosine
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

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CAS Number

789-61-7
分子量

283.31
分子式

C10H13N5O3S
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 130 mg/mL; 458.86 mM
SMILES

NC1=NC(=S)C2=C(N1)N(C=N2)[C@H]1C[C@H](O)[C@@H](CO)O1
化学全称

2-Amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione