Asperuloside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Asperuloside 是一种环烯醚萜，来源于蛇舌草，具有抗炎活性。Asperuloside 可抑制诱导型一氧化氮合酶 (iNOS)，抑制 NF-κB 和 MAPK 信号通路。

Asperuloside has anti-inflammatory activity.

Western Blot Analysis Cell Line:U937 cells Concentration:0-5 mM Incubation Time:24 h Result:Increased the cleaved Caspase-3, Caspase-9, and PARP, and Cyto-c release from mitochondria.Induced expression of GRP78, p-PERK, p-eIF2α, CHOP, p-IRE1, XBP1, ATF6 and cleaved Caspase-12

Animal Model:Rats consuming a high fat diet (HFD)Dosage:3 mg/day Administration:p.o., 0.3% in diet, daily, 12 weeks Result:Reduced body weight, energy intake, adiposity, blood glucose, and plasma insulin.

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Others

Other Targets

Others

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14259-45-1

414.36

C18H22O11

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (241.34 mM)

C(=O)(C)OCC1=C[C@@H]2OC(=O)C3=CO[C@H]([C@H]1[C@H]23)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO

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(-20℃)

With Ice Pack

≥ 2 years