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Cosmosiin

CAS No. 578-74-5

Cosmosiin ( Apigetrin )

产品货号. M18842 CAS No. 578-74-5

大波斯菊素可能通过增强脂联素分泌、胰岛素受体-β 酪氨酸磷酸化和 GLUT4 易位而有益于糖尿病并发症。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥748 有现货
10MG ¥1121 有现货
25MG ¥2213 有现货
50MG ¥3506 有现货
100MG ¥4842 有现货
200MG ¥6597 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥711 有现货

生物学信息

  • 产品名称
    Cosmosiin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    大波斯菊素可能通过增强脂联素分泌、胰岛素受体-β 酪氨酸磷酸化和 GLUT4 易位而有益于糖尿病并发症。
  • 产品描述
    Apigetrin is a flavanoid derivved from dandelions which may inhibit neuroinflammation in BV-2 microglia and have a neuroprotective effect in HT22 hippocampal cells. This molecule may also hinder cancer progression by inhibiting various pathways such as STAT3/JAK2.
  • 体外实验
    Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucosideprovoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucosideenhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.Apigenin 7-glucoside specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.
  • 体内实验
    ——
  • 同义词
    Apigetrin
  • 通路
    Others
  • 靶点
    Antioxidant
  • 受体
    HIV
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    578-74-5
  • 分子量
    432.38
  • 分子式
    C21H20O10
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : ≥ 30 mg/mL; 69.38 mM
  • SMILES
    C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O
  • 化学全称
    7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
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