nordihydroguaiareticacid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

去甲二氢愈创木酸 (NDGA) 是一种酚类抗氧化剂，存在于常绿沙漠灌木 Larrea tridentata (Sesse and Moc. ex DC) Coville（杂酚油灌木）的叶子和树枝中。

INSM-18, also known as nordihydroguaiaretic acid, NDGA and masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations.

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INSM18 | INSM-18, INSM 18, masoprocol

Others

Other Targets

Antioxidant

Cancer

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500-38-9

302.37

C18H22O4

>98% (HPLC)

DMSO : 75 mg/mL 248.05 mM;

CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O

4,4'-((2R,3S)-2,3-dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)

(-20℃)

With Ice Pack

≥ 2 years