Ziyuglycoside II

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

紫玉糖苷 II 通过细胞周期阻滞和细胞凋亡具有抗癌和抗胃癌和乳腺癌细胞的特性。

Ziyuglycoside II has anti-inflammation and antioxidation properties. Ziyuglycoside II has antibiosis, and homeostasis properties. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer and breast cancer cells, by cell cycle arrest and cell apoptosis.

Cell Viability Assay Cell Line:MDA-MB-435 cells Concentration:10, 20, 30, 40, 50, 60 μM Incubation Time:24 hours and 48 hours Result:The IC50 at 24 h and 48 h was 5.92 μM and 4.74 μM, respectively. Cell Cycle Analysis Cell Line:MDA-MB-435 cells Concentration:5, 10, 25 μM Incubation Time:24 hours Result:Induced G0/G1 and S phase arrest. Apoptosis Analysis Cell Line:MDA-MB-435 cells Concentration:5, 10, 25 μM Incubation Time:24 hours Result:The apoptotic rate was significantly increased in comparison to that of the control.Western Blot Analysis Cell Line:MDA-MB-435 cells Concentration:5, 10, 25 μM Incubation Time:24 hours Result:Treatment resulted in increased expressions of both p53 and p21.

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Neuroscience

GluR

Antioxidant

Cancer|Inflammation/Immunology

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35286-59-0

604.82

C35H56O8

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (82.67 mM)

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(CO6)O)O)O)C)C)C2C1(C)O)C)C(=O)O

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(-20℃)

With Ice Pack

≥ 2 years