Protostemonine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

原百部碱具有抗炎活性，可有效减弱 LPS 诱导的体外和体内炎症反应。

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM.Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.

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Others

Other Targets

Others

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27495-40-5

417.5

C23H31NO6

>98% (HPLC)

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CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C

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(-20℃)

With Ice Pack

≥ 2 years