2-Phthalimidehydroxy-acetic acid
CAS No. 134724-87-1
2-Phthalimidehydroxy-acetic acid ( —— )
产品货号. M26876 CAS No. 134724-87-1
2-邻苯二甲酰亚胺羟基乙酸是一种基于烷基链的 PROTAC 连接体,可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥281 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称2-Phthalimidehydroxy-acetic acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述2-邻苯二甲酰亚胺羟基乙酸是一种基于烷基链的 PROTAC 连接体,可用于 PROTAC 的合成。
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产品描述2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Raf
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研究领域——
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适应症——
化学信息
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CAS Number134724-87-1
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分子量221.168
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分子式C10H7NO5
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纯度>98% (HPLC)
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溶解度——
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SMILESOC(=O)CON1C(=O)c2ccccc2C1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Caroline Joy, et al. 1 -(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER.WO2015075483A1
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