Levodropropizine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Levodropropizine 是一种组胺受体抑制剂，Levodropropizine 是一种有效且耐受性良好的外周镇咳药。

Levodropropizine is a histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive drug.

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Animal Model:Pentylenetetrazol (PTZ)-induced status epilepticus in rats Dosage:20 and 40 mg/kg Administration:i.p.Result:Decreased Mean electroencephalogram (EEG) spike wave percentage score from 76.8% (placebo) to 13.1% (lower dose) and 7.6% (higher dose).Decreased Racine's Convulsion Scale (RCS) from a mean of 5.8 (placebo) to 1.83 (lower dose) and 1.16 (higher dose). Increased time to first myoclonic jerk (TFMJ) from a mean of 65.1 s (placebo), to 247.3 s (lower dose) and 295.5 s (higher dose).

Levodropropizine | DF 526 | DF-526 | DF526 | Levotuss

Endocrinology/Hormones

5-HT Receptor

HT

Inflammation/Immunology

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99291-25-5

236.31

C13H20N2O2

>98% (HPLC)

Ethanol: 47 mg/mL (198.89 mM); Water: 15 mg/mL (63.47 mM); DMSO: 47 mg/mL (198.89 mM)

OC[C@@H](O)CN1CCN(C2=CC=CC=C2)CC1

(S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol

(-20℃)

With Ice Pack

≥ 2 years