Betaxolol hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Betaxolol Hydrochloride 是一种选择性 β1 肾上腺素能受体阻滞剂，用于治疗高血压和青光眼。

Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.(In Vitro):Betaxolol hydrochloride is a cardioselective beta-adrenergic receptor blocking agent.(In Vivo):Betaxolol hydrochloride (5 mg/kg via i.p. injection) was administered at 24 and then 44 h following the final chronic cocaine administration. Animals treated with betaxolol during cocaine withdrawal exhibited a significant attenuation of anxiety-like behavior characterized by increased time spent in the open arms and increased entries into the open arms compared to animals treated with only saline during cocaine withdrawal. Betaxolol hydrochloride did not produce anxiolytic-like effects in control animals treated chronically with saline . Betaxolol hydrochloride produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade than either timolol or levobunolol. Betaxolol hydrochloride may be relatively safer to use in patients with reactive airway disease than either timolol or levobunolol.

Betaxolol hydrochloride is a cardioselective beta-adrenergic receptor blocking agent.

Betaxolol hydrochloride (5 mg/kg via i.p. injection) was administered at 24 and then 44 h following the final chronic cocaine administration. Animals treated with betaxolol during cocaine withdrawal exhibited a significant attenuation of anxiety-like behavior characterized by increased time spent in the open arms and increased entries into the open arms compared to animals treated with only saline during cocaine withdrawal. Betaxolol hydrochloride did not produce anxiolytic-like effects in control animals treated chronically with saline . Betaxolol hydrochloride produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade than either timolol or levobunolol. Betaxolol hydrochloride may be relatively safer to use in patients with reactive airway disease than either timolol or levobunolol .

Kerlone | SL 75212

Endocrinology/Hormones

Adrenergic Receptor

β1-adrenergic receptor

Cardiovascular Disease

——

63659-19-8

343.89

C18H30ClNO3

>98% (HPLC)

Ethanol: 69 mg/mL (200.64 mM); Water: 69 mg/mL (200.64 mM); DMSO: 69 mg/mL (200.64 mM)

CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl

Chemical Name: 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride

(-20℃)

With Ice Pack

≥ 2 years