Sulfinpyrazone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种促尿酸排泄化合物，用于降低痛风治疗中的血清尿酸盐水平。

A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.(In Vitro):Sulfinpyrazone (G-28315) stimulates fibrinolytic activity.(In Vivo):In rats with kaolin-induced paw oedema, Sulfinpyrazone (G-28315) is able to restore the markedly prolonged euglobulin clot lysis time in an oral dose of 30 mg/kg. Beside these effects, Sulfinpyrazone protects rabbits from arachidonate-induced sudden death after a single oral dose of 10-30 mg/kg.

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G-28315 | NSC 75925

Chromatin/Epigenetic

COX

COX| cMOAT

Other Indications

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57-96-5

404.48

C23H20N2O3S

>98% (HPLC)

Soluble in DMSO

O=C(C1CCS(C2=CC=CC=C2)=O)N(C3=CC=CC=C3)N(C4=CC=CC=C4)C1=O

1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)pyrazolidine-3,5-dione

(-20℃)

With Ice Pack

≥ 2 years