Acemetacin
CAS No. 53164-05-9
Acemetacin ( Acemetacin | Rantudil | K 708 | K-708 | K708 )
产品货号. M14887 CAS No. 53164-05-9
Acemetacin (Emflex) 是一种非甾体类抗炎药,是一种环氧合酶抑制剂吲哚美辛的乙醇酸酯。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ¥106 | 有现货 |
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| 200MG | ¥146 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥103 | 有现货 |
|
生物学信息
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产品名称Acemetacin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Acemetacin (Emflex) 是一种非甾体类抗炎药,是一种环氧合酶抑制剂吲哚美辛的乙醇酸酯。
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产品描述Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.(In Vitro):Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin.
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体外实验Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin. From Wikipedia.
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体内实验——
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同义词Acemetacin | Rantudil | K 708 | K-708 | K708
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通路Chromatin/Epigenetic
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靶点COX
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受体COX
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number53164-05-9
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分子量415.82
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分子式C21H18ClNO6
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纯度>98% (HPLC)
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溶解度Ethanol: 58 mg/mL warmed (139.48 mM); DMSO: 83 mg/mL (199.6 mM)
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SMILESO=C(OCC(O)=O)CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3
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化学全称1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chávez-Pi?a AE, et al. Br J Pharmacol, 2008, 155(6), 857-864.
产品手册
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