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Pregabalin
CAS No. 148553-50-8
Pregabalin ( CI-1008 | S-(+)-3-isobutylgaba )
产品货号. M12048 CAS No. 148553-50-8
Pregabalin (CI-1008) 是一种 GABA 的 3-异丁基衍生物，可选择性结合 alpha2delta (A2D) 亚基电压依赖性钙通道 (VDCC)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pregabalin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Pregabalin (CI-1008) 是一种 GABA 的 3-异丁基衍生物，可选择性结合 alpha2delta (A2D) 亚基电压依赖性钙通道 (VDCC)。
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产品描述Pregabalin (CI-1008) is a 3-isobutyl derivative of GABA that selectively binds to alpha2delta (A2D) subunit voltage-dependent calcium channels (VDCCs); prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.Epilepsy Approved.
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体外实验——
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体内实验——
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同义词CI-1008 | S-(+)-3-isobutylgaba
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通路GPCR/G Protein
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靶点Calcium Channel
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受体Calcium Channel
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研究领域Neurological Disease
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适应症Epilepsy
化学信息
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CAS Number148553-50-8
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分子量159.23
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分子式C8H17NO2
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)C[C@H](CN)CC(O)=O
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化学全称(S)-3-(Aminomethyl)-5-methylhexanoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Field MJ, et al. Br J Pharmacol. 1997 Aug;121(8):1513-22.
2. Field MJ, et al. J Pharmacol Exp Ther. 1997 Sep;282(3):1242-6.
3. Eutamene H, et al. J Pharmacol Exp Ther. 2000 Oct;295(1):162-7.
产品手册
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