Arbidol hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

阿比朵尔（乌米非诺韦）盐酸盐是一种广谱抗病毒化学制剂，可通过阻断病毒与宿主细胞膜的融合来抑制有包膜病毒进入细胞。

Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane. (In Vitro):Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus.(In Vivo):Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines.

Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus.

Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines. Animal Model:BALB/c mice were infected with A/FM/1/47 (H1N1) Dosage:45, 90, and 180 mg/kg Administration:p.o.; daily for 5 days Result:Decreased the transcription of cytokines in murine lung following the IFV A (H1N1) Infection.

Umifenovir

Microbiology/Virology

Influenza Virus

Influenza A virus

Infection

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131707-23-8

513.88

C22H25BrN2O3S·HCl

>98% (HPLC)

Ethanol: 22 mg/mL (42.81 mM); DMSO: 103 mg/mL (200.43 mM)

Cl.CCOC(=O)C1=C(CSC2=CC=CC=C2)N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12

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(-20℃)

With Ice Pack

≥ 2 years