Lamotrigine
CAS No. 84057-84-1
Lamotrigine ( BW 430C; Epilepax; Lamictal; LTG )
产品货号. M16122 CAS No. 84057-84-1
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder.
纯度: >98%(HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
200MG | ¥251 | 有现货 |
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500MG | ¥373 | 有现货 |
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1G | ¥583 | 有现货 |
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生物学信息
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产品名称Lamotrigine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder.
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产品描述Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring.
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同义词BW 430C; Epilepax; Lamictal; LTG
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT (human platelets); 5-HT (rat brain synaptosomes)
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number84057-84-1
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分子量256.09
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分子式C9H7Cl2N5
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纯度>98%(HPLC)
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溶解度Ethanol: 3 mg/mL (11.71 mM); DMSO: 10 mg/mL (39.04 mM)
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SMILESNC1=NC(N)=C(C2=CC=CC(Cl)=C2Cl)N=N1
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化学全称6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Ro 67-7476
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
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Dapoxetine HCl
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor used for the therapy of premature ejaculation.
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PRX-07034
PRX-07034 is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents.?PRX-07034 is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.