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JZL195

CAS No. 1210004-12-8

JZL195 ( JZL195; JZL-195; JZL 195 )

产品货号. M17194 CAS No. 1210004-12-8

JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥316 有现货
10MG ¥527 有现货
25MG ¥1126 有现货
50MG ¥2130 有现货
100MG ¥3208 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    JZL195
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.
  • 产品描述
    JZL195 is a potent and selective dual inhibitor of FAAH and monacylglycerol lipase (MAGL). JZL195 has greater anti-allodynic efficacy than selective FAAH, or MAGL inhibitors, plus a greater therapeutic window than a cannabinoid receptor agonist. JZL195 may have greater potential in alleviating neuropathic pain, compared to selective FAAH and MAGL inhibitors, or cannabinoid receptor agonists.
  • 同义词
    JZL195; JZL-195; JZL 195
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    FAAH; MAGL
  • 研究领域
    Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    1210004-12-8
  • 分子量
    433.46
  • 分子式
    C24H23N3O5
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 42 mg/mL. 96.89 mM
  • SMILES
    [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cc(Oc4ccccc4)ccc3)CC2)cc1
  • 化学全称
    4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Long JZ, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20270-5.
产品手册
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