JNJ-37822681 ( JNJ 37822681;JNJ37822681 )

产品货号. M27891 CAS No. 935776-74-2

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HNMR

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产品名称

JNJ-37822681
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.
产品描述

JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.(In Vivo):JNJ-37822681 occupied D2 receptors in rat brain at relatively low doses (ED50 = 0.39 mg/kg) and was effective in animal models of psychosis (e.g., inhibition of apomorphine-induced stereotypy or D-amphetamine/phencyclidine-induced hyperlocomotion).
同义词

JNJ 37822681;JNJ37822681
通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

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研究领域

——
适应症

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1.Zhihui Xiao, et al. A new flavanone glucoside from Abrus precatorius.Chemistry of Natural Compounds volume 48, pages 565-567 (2012).

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