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J-14
CAS No. 1043854-13-2
J-14 ( —— )
产品货号. M21559 CAS No. 1043854-13-2
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM).?J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin leading to cytotoxicity and cancer cell death.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥340 | 有现货 |
|
| 5MG | ￥551 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1280 | 有现货 |
|
| 50MG | ￥1960 | 有现货 |
|
| 100MG | ￥3329 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称J-14
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM).?J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin leading to cytotoxicity and cancer cell death.
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产品描述J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM).?J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin leading to cytotoxicity and cancer cell death.
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同义词——
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通路Others
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靶点Other Targets
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受体sulfiredoxin
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研究领域——
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适应症——
化学信息
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CAS Number1043854-13-2
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分子量517.04
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分子式C28H25ClN4O2S
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纯度>98% (HPLC)
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溶解度DMSO:260 mg/mL (502.86 mM; Need ultrasonic)
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SMILESOC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kim H et al. Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage. Free Radic Biol Med. 2016 Feb;91:264-74.
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