NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter.

3'-Hydroxypterostilbene a natural pterostilbene analogue effectively inhibits the growth of human colon cancer cells with IC50s of 9.0 40.2 and 70.9 μM for COLO 205 HCT-116 and HT-29 cells respectively by inducing apoptosis and autophagy.

SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM.