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IWP-O1
CAS No. 2074607-48-8
IWP-O1 ( —— )
产品货号. M20089 CAS No. 2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥437 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1393 | 有现货 |
|
| 25MG | ￥2406 | 有现货 |
|
| 50MG | ￥3718 | 有现货 |
|
| 100MG | ￥5322 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称IWP-O1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
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产品描述IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
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同义词——
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通路Wnt/Notch/Hedgehog
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靶点Porcupine
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受体Porcn
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研究领域——
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适应症——
化学信息
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CAS Number2074607-48-8
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分子量432.48
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分子式C26H20N6O
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纯度>98% (HPLC)
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溶解度DMSO: 100 mg/mL
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SMILESO=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1
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化学全称5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-123-triazol-1-acetamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.You L et al. Development of a triazole class of highly potent Porcn inhibitors. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5891-5895.
产品手册
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WNT-974
A potent and specific small-molecule Porcupine (PORCN) inhibitor with IC50 of 1 nM in the PORCN radioligand binding assay.
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IWP-O1
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
